Characteristic of The Main Causal Factors of Infertility
This article dedicated to fertility impairment, which is one of the most important problems in reproductive medicine, and solving ways for timely diagnosis and adequate therapy of couples suffering from infertility in order to not only to prevent the development of complications such as miscarriage, ectopic pregnancy, intrauterine infection, fetal hypoxia, fetal-placental dysfunction, etc. but also help to reduce reproductive losses and the birth of healthy progeny. It should be noted that works devoted to the problem of infertility in the region of Uzbekistan, where information on its frequency and structure is insignificant. In the population, such studies had not been conducted, and at the same time, judging by the appeal statistics, the number of infertile marriages had increased in recent years. During the experiment, there were determined main reasons, which straightforwardly lead to infertility, such as inflammatory diseases of the genital organs, hormonal disorders, man role in sterility, relative marriage etc.
Aitken, R. J., Baker, M. A., & Sawyer, D. (2003). Oxidative stress in the male germ line and its role in the aetiology of male infertility and genetic disease. Reproductive biomedicine online, 7(1), 65-70. https://doi.org/10.1016/S1472-6483(10)61730-0
Arnold, A. P., & Chen, X. (2009). What does the “four core genotypes” mouse model tell us about sex differences in the brain and other tissues?. Frontiers in neuroendocrinology, 30(1), 1-9. https://doi.org/10.1016/j.yfrne.2008.11.001
Frobenius, W., & Bogdan, C. (2015). Diagnostic value of vaginal discharge, wet mount and vaginal pH–an update on the basics of gynecologic infectiology. Geburtshilfe und Frauenheilkunde, 75(4), 355. 10.1055/s-0035-1545909
Greil, A. L. (1997). Infertility and psychological distress: a critical review of the literature. Social science & medicine, 45(11), 1679-1704. https://doi.org/10.1016/S0277-9536(97)00102-0
Mascarenhas, M. N., Flaxman, S. R., Boerma, T., Vanderpoel, S., & Stevens, G. A. (2012). National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Med, 9(12), e1001356. https://doi.org/10.1371/journal.pmed.1001356
Meehl, P. E. (1954). Clinical versus statistical prediction: A theoretical analysis and a review of the evidence. https://doi.org/10.1037/11281-000
Pushkarev, V. A., Mustafina, G. T., & Khusnutdinov Sh, M. Glandular hyperplasia of endometrium. Diagnotis, clinic, treatment.[Zhelezistaya giperplaziya endometriya. Diagnostika, klinika, lechenie]. Kreativnaya hirurgiya i onkologiya. 2013;(4): 23–7.
Rusz, A., Pilatz, A., Wagenlehner, F., Linn, T., Diemer, T., Schuppe, H. C., ... & Weidner, W. (2012). Influence of urogenital infections and inflammation on semen quality and male fertility. World journal of urology, 30(1), 23-30. https://doi.org/10.1007/s00345-011-0726-8
Thoma, M. E., McLain, A. C., Louis, J. F., King, R. B., Trumble, A. C., Sundaram, R., & Louis, G. M. B. (2013). Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach. Fertility and sterility, 99(5), 1324-1331. https://doi.org/10.1016/j.fertnstert.2012.11.037
Tournaye, H., Krausz, C., & Oates, R. D. (2017). Novel concepts in the aetiology of male reproductive impairment. The Lancet Diabetes & Endocrinology, 5(7), 544-553. https://doi.org/10.1016/S2213-8587(16)30040-7